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St. Louis on the Air
1:57 pm
Tue May 21, 2013

Genetics Counseling For Cancer And The Decision To Have Preventive Surgery

Credit (Courtesy: National Human Genome Research Institute)
DNA Double Helix
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Cancer is cruel and it impacts the lives of far too many people and their families.  According to the World Health Organization, breast cancer kills 458,000 people each year.

Recently, actress and director Angelina Jolie, in a New York Times op-ed entitled My Medical Choice, announced she received a double mastectomy in order to minimize her risk of getting breast cancer.

Jolie has a genetic predisposition to breast cancer.  Her mom died from the disease at the age of 56.

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Breast Cancer
2:31 pm
Fri December 7, 2012

Wash U. Research Findings Could Be Good News To Some Breast Cancer Patients

Credit (via Washington University in St. Louis/Shyam Kavuri, Ph. D.)
The top image shows untreated breast cancer cells with HER2 mutations. The bottom image shows how much these cells shrink after treatment with neratinib, an anti-HER2 drug currently in clinical trials.
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The findings of new breast cancer research from Washington University could result in effective treatment for 4,000 additional patients in the United States each year. Scientists made the discovery after analyzing DNA sequencing data from 1,500 patients.

The research appears in the latest edition of Cancer Discovery.

So what does this research mean?

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